hexokinase d — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T16479	PF-04937319		Others , Glucokinase
	PF-04937319 is an activator of glucokinase (EC50 =154.4 μM). PF-04937319 maintains glucose-lowering efficacy while mitigating the risk of hypoglycemia observed with many other glucokinase activators. PF-04937319 can be ...		Others , Glucokinase
T3104	Globalagliatin	LY2608204	Glucokinase
	Globalagliatin (LY2608204) has been used in trials studying the treatment of Diabetes Mellitus, Type 2.		Glucokinase
TQ0055	AMG-3969		Glucokinase
	AMG-3969 is an effective glucokinase-glucokinase regulatory protein interaction (GK-GKRP) disruptor (IC50: 4 nM).		Glucokinase
T3312	AM-2394	AM2394	Glucokinase
	AM-2394 is an effective and specific Glucokinase agonist (GKA, EC50: 60 nM), which catalyzes the phosphorylation of glucose to glucose-6-phosphate. AM-2394(AM2394) increases the affinity of GK for glucose by approximatel...		Glucokinase
T15159	Dorzagliatin	HMS5552	Glucokinase
	Dorzagliatin (HMS5552) is a dual-acting glucokinase (GK) activator. It also improves glycaemic control and pancreatic β-cell function in type 2 diabetes.		Glucokinase
T26712	AZD-1656	AZD 1656	Glucokinase
	AZD-1656 is a glucokinase activator (GKA) that can cause dose-limiting hypoglycemia in normal animals used in embryofetal development studies and type 2 diabetes.		Glucokinase
T12056	MK-0941 free base		Glucokinase
	MK-0941 free base is an orally active glucokinase activator, exhibiting strong glucose-lowering activity and is a potential therapeutic agent for treatment of type 2 diabetes.		Glucokinase
T19500	Palmitelaidic Acid	trans-Palmitoleic acid,9-trans-Hexadecenoic acid	Glucokinase , AMPK , PPAR
	Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue.		Glucokinase , AMPK , PPAR
T6742	2-Deoxy-D-glucose	2-Deoxy-D-arabino-hexose,2-deoxyglucose,D-Arabino-2-deoxyhexose,Ba 2758,NSC 15193,2-DG	Apoptosis , Hexokinase , HSV
	2-Deoxy-D-glucose (2-DG) is an analog of glucose, an inhibitor of glycolysis. 2-Deoxy-D-glucose has antiviral activity, as well as inhibitory cell proliferation and apoptosis-inducing activity.		Apoptosis , Hexokinase , HSV
T5113	L-GLUCOSE	L-(-)-Glucose	Others
	L-Glucose (L-(-)-Glucose) is an enantiomer of D-glucose. L-Glucose is not bioavailable to cells as an energy source because it cannot be phosphorylated by hexokinase.		Others
T4726	D-Glucose 6-phosphate sodium	G6P sodium salt,D-Glucose 6-phosphate sodium salt,Sodium Glucose-6-Phosphate	Others , Endogenous Metabolite
	In cells, D-glucose 6-phosphate (G6P) is generated when glucose is phosphorylated by hexokinase or glucokinase or by the conversion of glucose-1-phosphate by phosphoglucomutase during glycogenolysis. G6P lies at the begi...		Others , Endogenous Metabolite
T5069	D-Glucose 6-phosphate potassium salt		Others
	D-Glucose 6-phosphate potassium is the potassiu salt form of D-glucose 6-phosphate, which is a glucose sugar phosphorylated at the hydroxy group on carbon 6.		Others
T72092	2-Deoxy-D-glucose 6-phosphate disodium
	2-Deoxy-D-glucose 6-phosphate disodium, a derivative of glucose analog 2-Deoxy-D-glucose, is synthesized in mammalian cells through hexokinase activity on 2-DG. It functions as a competitive inhibitor of glucose metaboli...
T35683	2-deoxy-D-Glucose-13C6	2-deoxy-D-Glucose-13C6
	2-deoxy-D-Glucose-13C6is intended for use as an internal standard for the quantification of 2-deoxy-D-glucose by GC- or LC-MS. 2-deoxy-D-Glucose is a glucose antimetabolite and an inhibitor of glycolysis.1,2It inhibits h...